Personally I'd get rid of the useless stuff like the low level seeds you have in first picture for example, onion, potato, tomato etc... And the cake ingredients on bottom right corner.
From second picture I'd personally get rid of all the bolts except maybe rune, possibly make a "junk" tab for everything that you will never probably need.
I crossed over items that I'd get rid of. You could also make a place for ground blue dragon scales next to blue dragon scales.
Getting rid of like 40% of the stuff would also mean you'd probably have to re-arrange the leftover items a bit to make it look appealing again to you.